POU/TBP Cooperativity
نویسندگان
چکیده
منابع مشابه
Cooperativity in biological systems
Living organisms can sense and respond to external and internal stimuli. Response isdemonstrated in many forms including modulation of gene expression profiles, motility,secretion, cell death, etc. Nevertheless, all forms share a basic property: they depend on sensingsmall changes in the concentration of an effector molecule or subtle conformational changes ina protein and invoking the appropri...
متن کاملcooperativity in biological systems
living organisms can sense and respond to external and internal stimuli. response isdemonstrated in many forms including modulation of gene expression profiles, motility,secretion, cell death, etc. nevertheless, all forms share a basic property: they depend on sensingsmall changes in the concentration of an effector molecule or subtle conformational changes ina protein and invoking the appropri...
متن کاملCooperativity of allosteric receptors.
Cooperativity of ligand binding to allosteric receptors can be quantified using the Hill coefficient (nH) to measure the sigmoidal character of the binding curve. However, for measurements of the transition between conformational states, nH values can be misleading due to ambiguity of the reference state. For cooperative ligand binding, the reference state is a hyperbolic curve for a monomer wi...
متن کاملCooperativity in ionic liquids.
Cooperativity in ionic liquids is investigated by means of static quantum chemical calculations. Larger clusters of the dimethylimidazolium cation paired with a chloride anion are calculated within density functional theory combined with gradient corrected functionals. Tests of the monomer unit show that density functional theory performs reasonably well. Linear chain and ring aggregates have b...
متن کاملCooperativity in Pituitary Gonadotropes
The highly cooperative nature of Ca 2 -dependent exocytosis is very important for the precise regulation of transmitter release. It is not known whether the number of binding sites on the Ca 2 sensor can be modulated or not. We have previously reported that protein kinase C (PKC) activation sensitizes the Ca 2 sensor for exocytosis in pituitary gonadotropes. To further unravel the underlying me...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2002
ISSN: 1097-2765
DOI: 10.1016/s1097-2765(02)00597-x